Many of our undergraduate students, about 65-80 or so any given year, perform significant research in the various laboratories within the Biological Sciences Department. A number of these have made contributions significant enough for them to serve as co-authors on publications in scientific journals. Several of these students are co-authors on more than one paper, and some are even the first author of the publication. Many undergraduates also have served as co-authors on posters presented at national and international meetings. Some examples of the publications of which our undergraduates are co-authors and contributors to are given below, with the undergraduate students' names highlighted. In addition, powerpoint presentations of several recent undergraduate research projects can be found here.
Campbell, M. A., A. Rokas, and J. C. Slot (2012). Horizontal transfer and death of a fungal secondary metabolic gene cluster. Genome Biology and Evolution. 4: 289-293.
Coggins, S.A., T.Y. Estévez-Lao, and J.F. Hillyer. 2012. Increased survivorship following bacterial infection by the mosquito Aedes aegypti as compared to Anopheles gambiae correlates with increased transcriptional induction of antimicrobial peptides. Developmental and Comparative Immunology. 37(3-4):390-401.
Coffee RL Jr, Williamson AJ, Adkins CM, Gray MC, Page TL, Broadie K. In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation. Human Molecular Genetics 2012 Feb 15;21(4):900-15.
Erickson DM, Wood EA, Oliver KM, Billick I, & Abbot P. 2012. The effect of ants on the population dynamics of a protective symbiont of aphids, Hamiltonella defensa. Annals of the Entomological Society of America 105: 447-453.
Mandel J.R., E.V. McAssey, K.M. Roland, and D.E. McCauley. 2012. Mitochondrial gene diversity associated with the atp9 stop codon in natural populations of wild carrot (Daucus carota ssp. carota). Journal of Heredity 103: 418-425.
McDonald, M., Box, H.
, Bian, W., Kendall, A., Tycko, R., and Stubbs, G. (2012). Fiber diffraction data indicate a hollow core for the Alzheimer's Aβ 3-fold symmetric fibril. J. Mol. Biol. 423, 454-461.
Siller S.S. and Broadie K. Matrix metalloproteinases and minocycline: therapeutic avenues for fragile X syndrome. Neural Plasticity 2012:124548. Epub 2012 May 20.
Rushton E, Rohrbough J, Deutsch K, Broadie K. Structure-function analysis of endogenous lectin mind-the-gap in synaptogenesis. Developmental Neurobiology 2012 Aug;72(8):1161-79.
Singleton, C. K., Xiong, Y., Kirsten, J., and Pendleton, K. (2012) eIF2a kinases regulate development through the BzpR transcription factor in Dictyostelium discoideum. PloS One 7, e325000.
Zhang, H., A. Rokas, and J. C. Slot (2012). Two different secondary metabolism gene clusters occupied the same ancestral locus in fungal dermatophytes of the Arthrodermataceae. PLoS ONE 7: e41903.
Zhou B, DR Arnett, X Yu, A Brewster, GA Sowd, CL Xie, S Vila, D Gai, E Fanning, XS Chen. 2012. J Biol. Chem. 287, 26854-26866.
Bowman, R., Xiong, Y., Kirsten, J., and Singleton, C. K. (2011). eIF2a Kinases Control Chalone Production In Dictyostelium discoideum. Euk. Cell 10, 494-501.
Brett, C.L., L. Kallay, Z. Hua, R. Green, A. Chyou, Y. Zhang, T.R. Graham, M. Donowitz, R. Rao. 2011. Genome-wide analysis reveals the vacuolar pH-stat of Saccharomyces cerevisiae. PLoS One 6:e17619.
Chafee, M.E., C.N. Zecher, M.L Gourley, V.T. Schmidt, John H. Chen, S.R. Bordenstein, M.E. Clark, and S.R. Bordenstein. (2011) Decoupling of host-symbiont-phage coadaptations following transfer to a new host species. Genetics 187: 203-215.
Ciarleglio, C.M., Axley, J., Strauss B.R., Gamble, K.L. and McMahon D.G. (2011) Perinatal photoperiod imprints the circadian clock. Nature Neuroscience 14:25-27.
Clanton, J., Hope, K., and Gamse, J.T. Fgf signaling governs a cell fate decision by parapineal neurons, resubmitted after revision to the journal Development.
de Borsetti N.H., Dean B.J., Bain E.J., Clanton J.A., Taylor R.W., Gamse J.T. Light and melatonin schedule neuronal differentiation in the habenular nuclei. Developmental Biology 358:251-61, 2011.
Doll, C.A., Burkart, J.T., Hope, K.D., Halpern, M.E., Gamse, J.T. Subnuclear development of the zebrafish habenular nuclei requires ER translocon function. Developmental Biology 360:44-57, 2011.
J.M. Talley, D.C. DeZwaan, L.D. Maness, B.C. Freeman, and K.L. Friedman (2011) Stimulation of yeast telomerase activity by the Ever Shorter Telomeres 3 (Est3) subunit is dependent on direct interaction with the catalytic protein Est2. J. Biol. Chem. 286. 26431-26439.
Majumdar, D., C.A. Nebhan, L. Hu, B. Anderson, D.J. Webb. 2011. An APPL1/Akt Signaling Complex Regulates Dendritic Spine and Synapse Formation in Hippocampal Neurons. Mol. Cell. Neurosci. 46:633-644.
R.C.B. Bairley, G. Guillaume, L.R. Vega, and K.L. Friedman (2011) A mutation in the catalytic subunit of yeast telomerase alters primer/template alignment while promoting processivity and protein/DNA binding. J. Cell Sci., 124. 4241-52.
Robert W. Taylor, Jenny Y. Qi, Anna K. Talaga, Taylur P. Ma, Luyuan Pan, Clinton R. Bartholomew, Daniel J. Klionsky, Cecilia B. Moens, and Joshua T. Gamse Journal of Neuroscience, in press, 2011.
Siller S. S. and Broadie K. Neural circuit architecture defects in a Drosophila model of Fragile X syndrome are alleviated by minocycline treatment and genetic removal of matrix metalloproteinase. Disease Models & Mechanisms 2011 Oct;4(5):673-85.
Talley JM, DeZwaan DC, Maness LD, Freeman BC, Friedman KL. (2011) Stimulation of yeast telomerase activity by the ever shorter telomere 3 (Est3) subunit is dependent on direct interaction with the catalytic protein Est2. J Biol Chem. 286(30): 26431-9.
Taylor, R.W., Qi, J.Y., Talaga, A.K, Ma, T.P., Pan, L.P., Bartholomew, C.R., Klionsky, D.J., Moens, C.B., and Gamse, J.T., Asymmetric inhibition of Ulk2 causes left-right differences in habenular neuropil formation. Journal of Neuroscience 31:9869-78, 2011.
Andereck, J.W., J.G. King, and J.F. Hillyer. 2010. Contraction of the ventral abdomen potentiates extracardiac retrograde hemolymph propulsion in the mosquito hemocoel. PLoS ONE. 5(9):e12943.
Glenn, J.D., J.G. King, and J.F. Hillyer. 2010. Structural mechanics of the mosquito heart and its function in bidirectional hemolymph transport. Journal of Experimental Biology. 213(4):541-50.
Huang, H., B.E. Weiner, H. Zhang, B.E. Fuller, Y. Gao, B. Wile, K. Zhao, D. R. Arnett, W.J. Chazin, & E. Fanning. Structure of a DNA polymerase ïÂÂÂ¡-primase domain that docks on the SV40 helicase and activates the viral primosome. J. Biol. Chem. 285, 17112-17122 (2010). Asymmetric inhibition of Ulk2 causes left-right differences in habenular neuropil formation.
Janson EM, Peeden ER, Stireman JO, & Abbot. 2010. Complexity without co-evolution in a mutualistic symbiosis. Journal of Evolutionary Biology 23: 2212-2228.
Grogan K, Chhatre V, & Abbot P. 2010. The cost of conflict in aphid societies. Journal of Evolutionary Biology 23: 185-193.
McDonald, M., Kendall, A., Bian, W., McCullough, I., Lio, E., Havens, W.M., Ghabrial, S.A., and Stubbs, G. (2010). Architecture of the potyviruses. Virology 405, 309-313.
Pendergast JS, Yeom M, Reyes BA, Ohmiya Y, Yamazaki S (2010) Disconnected circadian and cell cycles in a tumor-driven cell line. Commun Integr Biol. 3:536-539. PMCID: PMC3038057.
Pendergast JS, Friday RC, Yamazaki S (2010) Photic Entrainment of Period Mutant Mice is Predicted from Their Phase Response Curves. J Neurosci. 30:12179-84. PMCID: PMC2943870.
Pendergast JS, Friday RC, Yamazaki S (2010) Distinct Functions of Period2 and Period3 in the Mouse Circadian System Revealed by In Vitro Analysis. PLoS ONE 5(1): e8552. doi:10.1371/journal.pone.0008552. PMCID: PMC2804141.
Knadler, J. and Page, T.L. (2009) Social Interactions and the circadian rhythm in locomotor activity in the cockroach Leucophaea maderae. Chronobiol. Intl. 26: 415-429.
Passarella RJ, Zhou L, Phillips JG, Wu H, Hallahan DE, Diaz R. (2009) Clinical Cancer Research:Recombinant peptides as biomarkers for tumor response to molecular targeted therapy. 15(20):6421-9,Epub 2009 Oct.13 PMID:19825959
Pendergast JS, Nakamura W, Friday RC, Hatanaka F, Takumi T, Yamazaki S (2009) Robust food anticipatory activity in BMAL1-deficient mice. PLoS ONE 4(3):e4860. PMCID: PMC2654093.
Abbot P, Grinath J, Brown J, Peeden E, Erickson D, & Billick I. 2008. Insect herbivore stoichiometry: The relative importance of host plants and ant mutualists. Ecological Entomology 33: 497-502.
Ciarleglio, C.M., K. Ryckman, S.V. Servick, A. Hida, S. Robbins, N. Wells, J. Hicks, S.A. Larson, J.P. Wiedermann, K. Carver, N. Hamilton, K.K. Kidd, J.R. Kidd, J.R. Smith, J. Friedlaender, D.G. McMahon, S. 2008.
Kendall, A., McDonald, M., Bian, W., Bowles, T., Baumgarten, S.C., Shi, J., Stewart, P.L., Bullitt, E., Gore, D., Irving, T.C., Havens, W.M., Ghabrial, S.A., Wall, J.S., and Stubbs, G. (2008). Structure of flexible filamentous plant viruses. J. Virol. 82, 9546–9554.
Kirsten, J., Xiong, Y. Davis, C.,
and Singleton, C.K. (2008). Subcellular localization of ammonium transporters in Dictyostelium discoideum
. BMC Cell Biology 9:71.
Neuronal loss of Drosophila NPC1a causes cholesterol aggregation and age-progressive neurodegeneration. Phillips SE, Woodruff EA 3rd, Liang P, Patten M, Broadie K.J Neurosci. 2008 Jun 25;28(26):6569-82.
Rubinson, E.H., Metz, A.H., O’Quin, J., and Eichman, B.F. (2008) A New Protein Architecture for Processing Alkylation Damaged DNA: The Crystal Structure of DNA Glycosylase AlkD. J. Mol. Biol., 381: 13-23.
Stubbs, G., Kendall, A., McDonald, M., Bian, W., Bowles, T., Baumgarten, S., McCullough, I., Shi, J., Stewart, P., Bullitt, E., Gore, D. and Ghabrial, S. (2008). Flexible filamentous virus structures from fiber diffraction. Powder Diffraction 23, 113-117.
Wegner,AM, Nebhan, CA, Lan,H., Majumdar, D, Meier,KM, Weaver, AM, Webb, D.(2008)N-WASP and the arp2/3 complex are critical regulators of actin in the development of dendritic spines and synapses. Journal of Biological Chemistry 283(23) 15912-15920
Williams, M.L. Summar, and C.H. Johnson. Genetic Differences in Human Circadian Clock Genes Among Worldwide Populations. J. Biol. Rhythms 23: 330-340. PMCID: PMC2579796.